Principles of Chemical Biology

This subject introduces the chemical logic of cellular processes, and the chemical methods used to probe and perturb them. Coverage includes: the major classes of biomolecules and their biosynthesis with a focus on molecular structure; biological catalysis (enzymes, enzyme kinetics and the roles of trace metals and co-factors); and chemical methods for studying interactions and deconvoluting biological systems. Also covered are chemical techniques for qualitative and quantitative analysis of cellular processes and biomolecular interactions; imaging techniques for non-invasive analysis; analytical techniques and equipment for biomolecular studies; and common molecular tools. A key aspect of this subject will be the use of case studies to explore how chemical approaches can be applied to illuminate the molecular features of biological systems. This will be covered in a small-group learning mode and involve both a written report and oral presentation.

学习化学与生物学交叉领域的基本原理。

• 1Critically analyse problems at the interface of chemistry and biology
• 2Explain the molecular basis of a range of biological processes
• 3Interpret biological data by applying diverse chemical principles
• 4Explain the principles of the key analytical methods used in chemical biology